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Clinical trials and Medical studies

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Clinical Trial by Dr. Valéria Burzuk

Notices about the experiences in connection with the Saltpipe used in the case of 10 patients suffering from Chronic Bronchitis, COPD and Asthma Bronchiales:
10 patients were using the Saltpipe in the period starting in October 2002, finishing in February 2003, for 2-3 months of duration.

These patients were suffering from respiratory illnesses; 3 of them suffered from chronic bronchitis, 7 of them from asthma bronchiales:
2 of these 7 people had severe bronchitis and COPD.

4 patients out of the 10 were females and 6 of them were males. 2 patient between the age of 50 & 55, 3 between the age 55 & 60, 2 of them were between 60 & 65, and only one of the patients was above 70.

Out of these 10 patients, 6 suffered from heart diseases, which aggrevated the applicability of antispasmodic sprays – for the bronchial tubes – because of the side effects which exert the functioning of the heart.

I was trying to choose patients whose illness was severe (chronic bronchitis, COPD, and/or asthma bronchiale).

The experiences of the patients show that the Saltpipe helps to dissolve sediments, helps in the process of discharge and in so doing, eases their breathing.

As a doctor, I found the Saltpipe a very effective, complementary tool in the therapy of patients with respiratory illnesses.

We can almost equalize the effects of the mineral-filled air inhaled through the Saltpipe with the effects of the salt caverns (apart from the fact that the temperature of air inhaled through the Saltpipe is identical with body temperature). Furthermore, it is more moderate from a financial point of view than the expenses of salt cavern therapies.

As a summary, I would like to conclude the following:

The secretion-discharge is easier and so, the breathing of the patient becomes more relieved. I also observed that the speed of the air-stream in the small bronchial tubes accelerated which results in easier breathing.

I find the application of the Saltpipe indisputably beneficial.

I owe you my gratitude – also in the name of my patients – for the Saltpipe

Dr. Valeria BuZuk


Hegyi Gabriella, MD PhD, Division Leader Specialist

Medical inspection of the inhaler set called the Saltpipe.

The inspection of the instrument requested by:
B.B. System Kereskedelmi és Szolgáltató Kft.
(B.B. System Ltd. for Commerce and Services in Budapest, Hungary)
1146 Budapest, Francia út 57/c. (repr.: Békefi Imre) Now B.B.System has changed to Sopipa Pharma Kft)

The date of arrival of the instrument to our institute:
01. 09. 2002

Description of the instrument:
A ceramic container, filled with a mixture of special salt crystals and minerals.

Application of the instrument:
Setting it in the way of the inhaled air it helps the easier penetrability of the upper respiratory tructs with a special inhaling opportunity.

The basics of the functioning of the instrument:
Inhalation is a special method for the local treatment of respiratory illnesses. The advantages of the inhalation method are:

Local effect
Higher salt concentration in the upper tructs
Fast results
The systematic effect is lower than in case of medication implied
orally or injected
The instrument employs only fully natural resources

The obtainable physiological effects are:

Eventually: bronchospasmolysis
In case of special material (minerals): antiphlogisticus effect

Indications of the application:

For the chronic illnesses of respiratory tructs (asthma, bronchiale)
For different forms of allergic rhinitis

In case of long term application of the set, the vital capacity intensifies and subjectively, it provides an improved general state of health.

Our Experiences:

For the proper way of application the user must be trained and the process must be controlled,
monitored later on.
With the remission of the patient’s condition, an individual dose must be defined with other expression:
the duration of application must be determined.
The hypocamnia, caused by the forced – too hard – inhalation must be avoided so the aquirement of the proper
technique is essential.
In order to avoid contamination, and in order to keep the instrument clean, only one patient should use one set.
During the application of the instrument, we did not change the dosage of the patients.
The voluntarily involved patients we randomly divided into the “treatment” and the “control” groups.
The “treatment” patients used the instrument several times a day for a determined period of time.
Weekly and after two months we examined the patients – with attention to iron – and vital capacity.

The application of the Saltpipe is effective even in case of chronic upper respiratory illnesses, but in these cases there was a need for medicinary supplementation also.

In case of the chronic illnesses, the patients reported about a subjectively easier breathing and inspirational experiences, which was officially confirmed by objective vital capacity measurements.

Based on the above mentioned statements, the outcome of the adjuvant application of the instrument has proven to be EFFECTIVE in many of the cases.

During the test period no side effects have been observed.

I suggest the application of the “Saltpipe” instrument as a complementive, supportive method with the following completion:

It must be distributed with a suitably informative and ethic description for users, which does not deceive the user and does not make him or her abandon the previously used traditional medicaments and treatment.

Budapest, 08. 10. 2002.

Dr. Hegyi Gabriella MD.PhD., Division Leader Specialist
Yamamoto Institute for Rehabilitation
Training Institute of Semmelweis University
(Complementive Medical Attendance)
Budapest, Hungary


The effect of a dry salt inhaler in adults with COPD.

Cernomaz TABolog SGMihăescu T.


Spitalul Clinic de Pneumoftiziologie Iaşi, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.



to evaluate the effects of a dry salt inhaler in adults with COPD (stages II and III).


All 35 patients were under correct treatment according to GOLD guidelines for at least two weeks prior to the start of the study. The patients were given dry salt inhalers (which generated dry 1-5 microm NaCl particles) and were asked to use them up to 30 minutes per day. Spirometry tests and six minutes walk tests were performed initially and after one, two and three months.


As far as spirometry results are concerned no statistically significant results were recorded. However we found out there was a statistically significant improvement in the six minutes walk test values and quality of life assessed by means of Saint George Respiratory Questionnaire. There were no serious adverse events. Minor adverse events were represented by sore throat sensation usually after prolonged exposure to salt (over 15 minutes continuously)–this improved promptly with temporarily discontinuation and no additional action was necessary.


Dry salt inhaler therapy may prove to be a useful adjuvant therapy in COPD as far as effort tolerance and quality of life is concerned. However further studies are probably needed to exclude a placebo effect which could not be quantified under present circumstances.

Source: http://www.ncbi.nlm.nih.gov/pubmed/18019972